What is the Eisinger Score?

The Eisinger Score is a tool recommended by the French National Cancer Institute (INCa) to identify whether family history of breast and ovarian cancer warrants discussion with a physician.

BOADICEA is a mathematical model developed by the University of Cambridge, used by genetic oncologists to precisely assess the probability of BRCA1, BRCA2, PALB2 mutations and the absolute risk of breast and ovarian cancer.

What is the difference between the two tools?

The Eisinger Score is a simple orientation tool for the general public — it identifies situations worth discussing with a doctor. BOADICEA is a complex professional tool used by specialists to precisely quantify risk. They are complementary, not competing.

Eisinger Score & BOADICEA — Hereditary Breast Cancer Risk Tools

Understand before acting

First a signal.
Then a measure.

Assessing hereditary risk happens in two stages. First, identify situations that warrant attention — that is the Eisinger Score. Then, if necessary, precisely quantify that risk — that is BOADICEA. These two tools are not aimed at the same audience.

A family history is not a sentence.
It is information — that needs interpreting.

The two reference tools

Eisinger Score
and BOADICEA

One for everyone, the other for specialists.

Eisinger Score

Recommended by the French National Cancer Institute (INCa) — orientation tool towards genetic oncology consultation

What it is

A simple tool to identify whether family history of breast and ovarian cancer warrants particular attention. It does not measure risk in percentages — it flags situations that are worth discussing.

What it takes into account

The number of cases on the maternal and paternal sides
The degree of kinship — a mother counts more than a cousin
Age at diagnosis — a young-onset cancer is a stronger signal
Cases of ovarian cancer
A bilateral cancer or cancer in a man

A high score is not a diagnosis. The vast majority of women with a high score do not carry a genetic mutation. It is an invitation to discuss — not an alert.

BOADICEA

Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm — University of Cambridge, United Kingdom

What it is

A mathematical model used by genetic oncologists to precisely assess hereditary risk. The reference tool in the SENORIF 2025-2026 guidelines (Institut Curie, Gustave Roussy, AP-HP) and the only tool of its kind with European CE marking.

What it calculates

Probability of mutations on BRCA1, BRCA2, PALB2, CHEK2, ATM
Absolute risk of breast cancer at 10 years and lifetime
Absolute risk of ovarian cancer
Integration of breast density and genetic profile

🔒Professional tool, not accessible independently. If your physician considers an assessment by this tool useful, they will refer you to a genetic oncologist.

Complementary

The link between the two tools

The Eisinger Score and BOADICEA are not competing — they are complementary. One identifies situations that warrant attention, the other quantifies risk when a specialist consultation confirms that interest.

In most cases, the process stops at the first level: the Eisinger Score is reassuring, and no further investigation is necessary.

Take the next step

Assess your family history
in 6 questions

The questionnaire uses the Eisinger Score to explore your family history, simply and entirely confidentially. No data is recorded.

Start the questionnaire

Confidential · Local calculation in your browser · No account creation · No data recorded

Hereditary risk Eisinger & BOADICEA Dr Jérémie Zeitoun · Surgeon Paris 8th